Actinomycetoma .

ActinomycetomaActinomycetoma is a skin disease, in case that wasn’t apparent. Technically, its a chronic, specific, granulomatous, progressive inflammatory disease of bacteriological origin. None of those things mean good stuff, in case that wasn’t apparent.

The disease is common in Africa, India, and Central and South America, and is characterized by tumefaction and formation of sinus tracts. The sinuses usually discharge purulent and seropurulent exudate containing grains. It may spread to involve the skin and the deep structures resulting in destruction, deformity and loss of function, very occasionally it could be fatal. Without exception, you end up wishing it were.

There are several clinical treatments available for this disease, that include surgery, ketoconazole, voriconazole, itraconazole and amputation. Unfortunately, there is no sure-fire treatment available at this date.